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fiú Ernest Shackleton Komoly overall mutation load and p53 mutations Nád kompenzálni Hatékonyság

Evaluating the prognostic significance of p53 and TP53 mutations in  HPV-negative hypopharyngeal carcinoma patients: a 5-year follow-up  retrospective study | BMC Cancer | Full Text
Evaluating the prognostic significance of p53 and TP53 mutations in HPV-negative hypopharyngeal carcinoma patients: a 5-year follow-up retrospective study | BMC Cancer | Full Text

Frequency of p53 mutations in human cancers. (A) Schematic picture... |  Download Scientific Diagram
Frequency of p53 mutations in human cancers. (A) Schematic picture... | Download Scientific Diagram

Frontiers | Promising New Tools for Targeting p53 Mutant Cancers: Humoral  and Cell-Based Immunotherapies
Frontiers | Promising New Tools for Targeting p53 Mutant Cancers: Humoral and Cell-Based Immunotherapies

Mutant p53 achieved Gain-of-Function by promoting tumor growth and immune  escape through PHLPP2/AKT/PD-L1 pathway
Mutant p53 achieved Gain-of-Function by promoting tumor growth and immune escape through PHLPP2/AKT/PD-L1 pathway

Mutations in TP53 and other heterogeneous genes help to distinguish  metastases from new primary malignancies | medRxiv
Mutations in TP53 and other heterogeneous genes help to distinguish metastases from new primary malignancies | medRxiv

Evaluating the prognostic significance of p53 and TP53 mutations in  HPV-negative hypopharyngeal carcinoma patients: a 5-year follow-up  retrospective study | BMC Cancer | Full Text
Evaluating the prognostic significance of p53 and TP53 mutations in HPV-negative hypopharyngeal carcinoma patients: a 5-year follow-up retrospective study | BMC Cancer | Full Text

Cancers | Free Full-Text | TP53 Combined Phenotype Score Is Associated with  the Clinical Outcome of TP53-Mutated Myelodysplastic Syndromes
Cancers | Free Full-Text | TP53 Combined Phenotype Score Is Associated with the Clinical Outcome of TP53-Mutated Myelodysplastic Syndromes

IJMS | Free Full-Text | Do Mutations Turn p53 into an Oncogene?
IJMS | Free Full-Text | Do Mutations Turn p53 into an Oncogene?

Analysis of P53 mutations and their expression in 56 colorectal cancer cell  lines | PNAS
Analysis of P53 mutations and their expression in 56 colorectal cancer cell lines | PNAS

Gain of function in somatic TP53 mutations is associated with immune‐rich  breast tumors and changes in tumor‐associated macrophages - Behring - 2019  - Molecular Genetics & Genomic Medicine - Wiley Online Library
Gain of function in somatic TP53 mutations is associated with immune‐rich breast tumors and changes in tumor‐associated macrophages - Behring - 2019 - Molecular Genetics & Genomic Medicine - Wiley Online Library

Omics analyses of a somatic Trp53R245W/+ breast cancer model identify  cooperating driver events activating PI3K/AKT/mTOR signaling | PNAS
Omics analyses of a somatic Trp53R245W/+ breast cancer model identify cooperating driver events activating PI3K/AKT/mTOR signaling | PNAS

Biomolecules | Free Full-Text | p53's Extended Reach: The Mutant p53  Secretome
Biomolecules | Free Full-Text | p53's Extended Reach: The Mutant p53 Secretome

LRP1B or TP53 mutations are associated with higher tumor mutational burden  and worse survival in hepatocellular carcinoma
LRP1B or TP53 mutations are associated with higher tumor mutational burden and worse survival in hepatocellular carcinoma

TP53 mutation spectrum in primary colorectal cancers. a Proportion of... |  Download Scientific Diagram
TP53 mutation spectrum in primary colorectal cancers. a Proportion of... | Download Scientific Diagram

TP53 mutational landscape of metastatic head and neck cancer reveals  patterns of mutation selection - eBioMedicine
TP53 mutational landscape of metastatic head and neck cancer reveals patterns of mutation selection - eBioMedicine

The p53 network: cellular and systemic DNA damage responses in cancer and  aging: Trends in Genetics
The p53 network: cellular and systemic DNA damage responses in cancer and aging: Trends in Genetics

Acetylation halts missense mutant p53 aggregation and rescues tumor  suppression in non-small cell lung cancers - ScienceDirect
Acetylation halts missense mutant p53 aggregation and rescues tumor suppression in non-small cell lung cancers - ScienceDirect

Overall survival curves of patients with p53 mutation results. (A) p53... |  Download Scientific Diagram
Overall survival curves of patients with p53 mutation results. (A) p53... | Download Scientific Diagram

TP53 exon-6 truncating mutations produce separation of function isoforms  with pro-tumorigenic functions | eLife
TP53 exon-6 truncating mutations produce separation of function isoforms with pro-tumorigenic functions | eLife

Implications of driver genes associated with a high tumor mutation burden  identified using next‑generation sequencing on immunotherapy in  hepatocellular carcinoma
Implications of driver genes associated with a high tumor mutation burden identified using next‑generation sequencing on immunotherapy in hepatocellular carcinoma

Mutational processes shape the landscape of TP53 mutations in human cancer  | Nature Genetics
Mutational processes shape the landscape of TP53 mutations in human cancer | Nature Genetics

Germline TP53 mutations undergo copy number gain years prior to tumor  diagnosis | Nature Communications
Germline TP53 mutations undergo copy number gain years prior to tumor diagnosis | Nature Communications

A TP53-Associated Immune Prognostic Signature for the Prediction of Overall  Survival and Therapeutic Responses in Muscle-Invasive Bladder Cancer -  Frontiers
A TP53-Associated Immune Prognostic Signature for the Prediction of Overall Survival and Therapeutic Responses in Muscle-Invasive Bladder Cancer - Frontiers

Low-burden TP53 mutations in CLL: clinical impact and clonal evolution  within the context of different treatment options - ScienceDirect
Low-burden TP53 mutations in CLL: clinical impact and clonal evolution within the context of different treatment options - ScienceDirect

TP53 mutations predict poor response to immunotherapy in patients with  metastatic solid tumors - Kim - 2023 - Cancer Medicine - Wiley Online  Library
TP53 mutations predict poor response to immunotherapy in patients with metastatic solid tumors - Kim - 2023 - Cancer Medicine - Wiley Online Library

Survival of patients with p53 mutations in the DNA-binding motifs... |  Download Scientific Diagram
Survival of patients with p53 mutations in the DNA-binding motifs... | Download Scientific Diagram

Targeting a neoantigen derived from a common TP53 mutation | Science
Targeting a neoantigen derived from a common TP53 mutation | Science