fiú Ernest Shackleton Komoly overall mutation load and p53 mutations Nád kompenzálni Hatékonyság
Evaluating the prognostic significance of p53 and TP53 mutations in HPV-negative hypopharyngeal carcinoma patients: a 5-year follow-up retrospective study | BMC Cancer | Full Text
Frequency of p53 mutations in human cancers. (A) Schematic picture... | Download Scientific Diagram
Frontiers | Promising New Tools for Targeting p53 Mutant Cancers: Humoral and Cell-Based Immunotherapies
Mutant p53 achieved Gain-of-Function by promoting tumor growth and immune escape through PHLPP2/AKT/PD-L1 pathway
Mutations in TP53 and other heterogeneous genes help to distinguish metastases from new primary malignancies | medRxiv
Evaluating the prognostic significance of p53 and TP53 mutations in HPV-negative hypopharyngeal carcinoma patients: a 5-year follow-up retrospective study | BMC Cancer | Full Text
Cancers | Free Full-Text | TP53 Combined Phenotype Score Is Associated with the Clinical Outcome of TP53-Mutated Myelodysplastic Syndromes
IJMS | Free Full-Text | Do Mutations Turn p53 into an Oncogene?
Analysis of P53 mutations and their expression in 56 colorectal cancer cell lines | PNAS
Gain of function in somatic TP53 mutations is associated with immune‐rich breast tumors and changes in tumor‐associated macrophages - Behring - 2019 - Molecular Genetics & Genomic Medicine - Wiley Online Library
Omics analyses of a somatic Trp53R245W/+ breast cancer model identify cooperating driver events activating PI3K/AKT/mTOR signaling | PNAS
LRP1B or TP53 mutations are associated with higher tumor mutational burden and worse survival in hepatocellular carcinoma
TP53 mutation spectrum in primary colorectal cancers. a Proportion of... | Download Scientific Diagram
TP53 mutational landscape of metastatic head and neck cancer reveals patterns of mutation selection - eBioMedicine
The p53 network: cellular and systemic DNA damage responses in cancer and aging: Trends in Genetics
Acetylation halts missense mutant p53 aggregation and rescues tumor suppression in non-small cell lung cancers - ScienceDirect
Overall survival curves of patients with p53 mutation results. (A) p53... | Download Scientific Diagram
TP53 exon-6 truncating mutations produce separation of function isoforms with pro-tumorigenic functions | eLife
Implications of driver genes associated with a high tumor mutation burden identified using next‑generation sequencing on immunotherapy in hepatocellular carcinoma
Mutational processes shape the landscape of TP53 mutations in human cancer | Nature Genetics
Germline TP53 mutations undergo copy number gain years prior to tumor diagnosis | Nature Communications
A TP53-Associated Immune Prognostic Signature for the Prediction of Overall Survival and Therapeutic Responses in Muscle-Invasive Bladder Cancer - Frontiers
Low-burden TP53 mutations in CLL: clinical impact and clonal evolution within the context of different treatment options - ScienceDirect
TP53 mutations predict poor response to immunotherapy in patients with metastatic solid tumors - Kim - 2023 - Cancer Medicine - Wiley Online Library
Survival of patients with p53 mutations in the DNA-binding motifs... | Download Scientific Diagram
Targeting a neoantigen derived from a common TP53 mutation | Science